Aim: In this study, it was aimed to investigate that communication skills and affecting factors of nursing student participating to clinical practice. Material and Methods: Our research conducted as crosssectional and descriptive features at the Trakya University, Faculty of Health Sciences between February and March 2014. One hundred and seventy-nine 2nd, 3rd, and 4th year nursing students who learned communication course, volunteered to study and participated into clinical practice were included. Socio-demographic and communication characteristics were collected by using a survey form designed by researchers and communication skills of students were obtained by using “Communication Skills Inventory”. Results: Average age was 20.7 ± 1.1, 90.5% was women, alcohol consumption rate was 12.8%, 87.2% thought that their communication with people was good, 91.1% thought that their communication with patients was good, 17.9% had problems communicating with patients. 59.2% of the students thought that negative behavior of health staff in clinical practices negatively affected to their communication with the patient. The highest subscale score of the Communication Skills Inventory was cognitive skills (59.1 ± 6.2) while the lowest subscale score was emotional skills (53.0 ± 5.5). Cognitive skills score of students who not used alcohol (59.5 ± 6.0) was significantly higher than those used alcohol (56.2 ± 6.6) (P = 0.035). "Cognitive skills (p = 0.012)," "behavioral skills (p = 0.020)" and "total skills (p = 0.046)" scores of students thinking that learned communication lessons in the school was helpful were significantly higher, however, it was not significantly differ in "emotional skills (p = 0.448)" score. "Behavioral skills" score was significantly higher (p = 0.018) in students thought that their communication with people was good. Similarly, "behavioral skills" score was also significantly higher (p = 0.010) in students thought that their communication with patients was good. Conclusion: When the communication skills of nursing student participating to clinical practice are evaluated, individual behavioral skills is higher in students thought that their communication with patients and people was good and cognitive skills is higher in students who not used alcohol. Also, thinking that learned communication lessons in the school were helpful improves overall communication skills upgrading of cognitive and behavioral skills.