Aim: This research was conducted to examine hand hygiene compliance and hospital infections. Method: The study's universe consisted of reports of infection reports and hand hygiene monitoring reports prepared for the infection control committee in the 3-month period between January 1 and December 31, 2013 at the 9-bed mixed intensive care unit of the Army Training and Research Hospital. These data were obtained from hospital infections, infectious diseases and clinical microbiology specialists in the intensive care unit, and active surveillance methods based on laboratory and patient by infection control nurses. 433 patients, hospital infection rates calculated on 3361 patient days (prepared in 1-year 3-month period), and reported hand hygiene compliance rates on a total of 30 people in the same period were used. Percentage distribution was used in the evaluation of the data. Results: In the observation hand hygiene compliance was found 66.7% compliance rate group of doctors, nurses and midwivesi compliance rate compliance rate of 73.9% and the cleaning staff, 66.7%. In this study,infection rates have been found 34%infection rate of ventilator-associated pneumonia, urinary catheteris associated urinary tract infection rate,12.9%, and central venous catheter-related blood stream infection ratewas 7.9 %. Conclusion: Due to high hospital infections, it is advisable to increase the hand hygiene compliance rates and to implement effective hand hygiene.