Objective: This study is a descriptive research planned with an aim of determining the opinions of university students regarding blood and organ donation. Method: Students of Health High School, Vocational High School, Faculty of Economics and Administrative Sciences which are extensions of Selçuk University participated in the carried on research between the dates 30.03.2015 and 05.05.2015, and the study was carried out with the students (n=400) who voluntarily accepted to participate in the research before the sample election. The acquired data were evaluated with the SPSS 17.0 package software. Besides the evaluation of the data with numbers and percentages, Chi Square Test was used in comparing the students’ sexes and schools, and their characteristics regarding blood and organ donation, and the students’ desire of donating blood and organs. Findings: The ages of the students participating in the study varied between 17 and 25 and the arithmetic average was 20.59±1.27. 72.6 % percent of the study consisted of female students and 33.1% of the students were Vocational High School students. Conclusion: At the end of the conducted research it was determined that the condition for blood donation changed according to sexes. There is a statistically significant relationship between sex and the desire of donating organs, and most of the Health High School Students want to donate their blood. Organizing events concerned with the importance of blood and organ donation such as educations, meetings, symposiums and conferences; and bringing donation campaigns into action in which the youth can actively participate would be effective in increasing the university youth’s and society’s sensitivity about blood and organ donation.