Aim: The aim of the study was to examine carpal tunnel syndrome symptoms and functional status in office workers. Material and Method: This study is a descriptive research. The population of this research is comprised of people working in two different buildings private institutions in the city of Istanbul. The research was conducted between the dates of November 2015-May 2016. The population is comprised of 700 workers. It is aimed to reach whole population without sampling, but office workers intense worked and they didn’t want to participate, so this research was completed by contacting with 153 workers who are voluntary for this research. Individuals were informed about the research and verbal consents were obtained for the research. Socio-Demographic Questionnaire and Boston Carpal Tunnel Syndrome Questionnaire were used as data collection tools. Results: The average age of the participants was 33.62±8.22, 51.6% were woman, 50.3% were marriage, 12.4% were diagnosed with hand and wrist disorders. The mean score of the Symptom Severity Scale of Boston Carpal Tunnel Syndrome Questionnaire was 1.34±4.46 (min=1, max=3) and the mean score of Functional Status Scale was 1.24±0.40 (min=1, max=3.5). 62.1% of the workers stated that they did not have difficulty in their functions and 33.3% stated that they were slightly difficult. When examined in terms of symptoms; it was found that 42.5% of the workers did not have signs for carpal tunnel syndrome, 47% were mild, and 9.8% were medium. There was a significant positive correlation between the symptom severity scale and the functional status scale scores (r=.67, p=0.00). As carpal tunnel symptoms increased, functional capacity insufficient increased.