Purpose: This research is planned as a descriptive to determine of the knowledge and practices of mothers of aged 0-6 years old inpatient children in pediatry clinics. Methods: The research universe is consisted between October 2012 and March 2013 by the mothers having 0-6 age group children staying in child clinical in Research Hospital; and the sampling is done by universe known group chosen with sampling method with the help of 235 mothers voluntarily accepting to take part in this research. Data was collected using a questionnaire prepared by examining the literature by researchers and "0-6 Year Old Children's Mothers' Identification Scale Security Measures Towards Home Accidents". For data evaluation SPSS (Statistical Packagef Social Sciences) for Windows 20.0 program; for statistical analysis Shapiro-Wilk, Kruskal Wallis, Mann-Whitney U and ki-kare tests are preferred. Results: According to the results, the average age of the participating mothers is 30(±5,73) years, %15,7 of them are employed and %49,4 of them have elementary or lower school education level. The average age for children was 24 (±21,99) months and %54,9 was male. %30,2 of children who are subject to the research have at least once been subject to a home accident. Any statistically meaningful relevance between the occurrence frequency of home accident and mothers’ age, or gender of child has not been observed (p>0,05). The majority of the children to have home accident have been observed to be between 1-3 ages (%56,3). %55 of the home accident occurring as falls and %62,5 of them happen in living room of home. After the accident has happened %60 of all families applied to a health care provider, %36,3 of mothers took measures about home accidents, The education level of parents, total monthly income, existence of a private room for child, sleeping environment of the child, correct toy selection, first aid and home accidents education of mothers have been observed to have a meaningful relation with mothers’ scaling score (p<0,05). Conclusion: Increase the awareness of family by nurses to provide safe home environment for hospitalized children by educating the family home accidents, it is advisable to consider the families of education in the socio-cultural level.