Aim: The aim of this study is to determine locus of control of school of health students of a university and some related factors. Material and Method: This cross sectional study was conducted with 198 students in school of health on June-20145 Data of the study was collected with a questionnaire including questions for sociodemographic status and the Rotter Internal External Locus of Control Scale, Health Perception Scale , Beck Depression Inventory (Scale) (BCI), Academic Motivation Scale, Ten-Item Personality Inventory (Scale). Frequencies, one way anova and independent samples t test were used with SPSS 16.0 (program for statistical analysis of data). A value of p<0,05 was considered statistically significant. Results: Mean age of students was 20,07±1,8 (min:18; max:34) and 52% of the students were female. The students had external locus of control. It was determined that Rotter Internal External Locus of Control Scale total mean score of female students were statistically higher than male students (p= 0,04). Conclusion: Depression, sense of responsibility, amotivation were determined as the important variables related the locus of control for university students.