Objective: The aim of this study is to determine the level of loneliness in bed-dependent conscious persons at home. Method: This descriptive study was carried out with 71 bed- dependent conscious persons with voluntary participation out of 80 persons affiliated to 18 family healthcare centers located in the city center of Trabzon in 2 May-30 June 2017. The data were collected using a questionnaire including 11 questions about the characteristics of the persons and the factors affecting the loneliness and the University of California, Los Angeles (UCLA) loneliness scale that include 20 questions. Findings: It was determined that 75.7% of the bed-dependent persons were female, 46.4% were 50-71 years old, 29.5% had bed dependence- related brain hemorrhage and the mean loneliness scale was high (61.18 ± 4.40). The factors affecting loneliness were found as gender, age, marital status, those living at home, having children, the quality of visitors, visit frequency, the level of care needs and the way to share feelings. There was a significant relationship between loneliness and gender, age, marital status, having children and the characteristics of the people living at home (p <0.05). Conclusion and Recommendations: The study showed that the vast majority of bed-dependent patients at home felt themselves lonely. It is suggested that health professionals should make home visits in a planned and programmed manner and reorganize the health policies to support the psychological, social and care needs of every bed-dependent persons, especially the conscious ones.